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Molecular Systems Biology - 版本历史
2026-04-09T17:24:55Z
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2026-02-03T02:34:46Z
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<strong>Molecular Systems Biology</strong>（MSB）是由 <strong>[[EMBO]] (欧洲分子生物学组织)</strong> 拥有并通过 <strong>[[EMBO Press]]</strong> 出版的同行评审科学期刊。作为系统生物学领域的顶级刊物，MSB 致力于发表具有高影响力的研究，重点关注生物系统的动态属性、功能和行为。该期刊是 <strong>[[Systems Biology]] (系统生物学)</strong>、<strong>[[Synthetic Biology]] (合成生物学)</strong> 以及 <strong>[[Quantitative Biology]] (定量生物学)</strong> 领域的旗舰平台。MSB 自 2005 年创刊以来，一直是完全的 <strong>[[Open Access]] (开放获取)</strong> 期刊，并以其首创的“透明评审流程” (Transparent Review Process) 而闻名。<br />
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<div style="font-size: 1.2em; font-weight: bold; letter-spacing: 1.2px;">MSB</div><br />
<div style="font-size: 0.7em; opacity: 0.85; margin-top: 4px; white-space: nowrap;">Molecular Systems Biology (点击展开)</div><br />
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<div style="font-size: 0.8em; color: #64748b; margin-top: 12px; font-weight: 600;">系统生物学旗舰期刊</div><br />
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<th colspan="2" style="padding: 8px 12px; background-color: #e0f2fe; color: #1e40af; text-align: left; font-size: 0.9em; border-top: 1px solid #bae6fd;">期刊参数</th><br />
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<th style="text-align: left; padding: 6px 12px; background-color: #f8fafc; color: #475569; border-bottom: 1px solid #e2e8f0; width: 40%;">ISO 缩写</th><br />
<td style="padding: 6px 12px; border-bottom: 1px solid #e2e8f0; color: #0f172a;">Mol. Syst. Biol.</td><br />
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<th style="text-align: left; padding: 6px 12px; background-color: #f8fafc; color: #475569; border-bottom: 1px solid #e2e8f0;">创刊年份</th><br />
<td style="padding: 6px 12px; border-bottom: 1px solid #e2e8f0; color: #0f172a;">2005年</td><br />
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<th style="text-align: left; padding: 6px 12px; background-color: #f8fafc; color: #475569; border-bottom: 1px solid #e2e8f0;">出版商</th><br />
<td style="padding: 6px 12px; border-bottom: 1px solid #e2e8f0; color: #1e40af;">[[EMBO Press]]</td><br />
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<th style="text-align: left; padding: 6px 12px; background-color: #f8fafc; color: #475569; border-bottom: 1px solid #e2e8f0;">出版模式</th><br />
<td style="padding: 6px 12px; border-bottom: 1px solid #e2e8f0; color: #16a34a;">[[Open Access]] (OA)</td><br />
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<td style="padding: 6px 12px; border-bottom: 1px solid #e2e8f0; color: #0f172a;">> 10.0 (长期高影响)</td><br />
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<th style="text-align: left; padding: 6px 12px; background-color: #f8fafc; color: #475569; border-bottom: 1px solid #e2e8f0;">核心领域</th><br />
<td style="padding: 6px 12px; border-bottom: 1px solid #e2e8f0; color: #1e40af;">[[Systems Biology]]</td><br />
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<td style="padding: 6px 12px; border-bottom: 1px solid #e2e8f0; color: #0f172a;">[[Synthetic Biology]]<br>[[Computational Biology]]</td><br />
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<td style="padding: 6px 12px; border-bottom: 1px solid #e2e8f0; color: #0f172a;">1744-4292</td><br />
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<th style="text-align: left; padding: 6px 12px; background-color: #f8fafc; color: #475569;">官方网站</th><br />
<td style="padding: 6px 12px; color: #0f172a;"><a href="https://www.embopress.org/journal/msb" style="color:#2563eb; text-decoration:none;">embopress.org/msb</a></td><br />
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MSB 的核心理念是超越还原论（即仅研究单个基因或蛋白质），转向从<strong>系统层面</strong>理解生物学。<br />
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<h3 style="margin-top: 0; color: #1e40af; font-size: 1.1em;">重点收录方向</h3><br />
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<li style="margin-bottom: 8px;"><strong>[[Omics]] 数据整合：</strong> 将基因组、转录组、蛋白质组和代谢组数据结合，构建调控网络。</li><br />
<li style="margin-bottom: 8px;"><strong>[[Synthetic Biology]]：</strong> 设计和构建新的生物部件、设备和系统。</li><br />
<li style="margin-bottom: 8px;"><strong>[[Quantitative Biology]]：</strong> 利用数学建模和计算模拟来预测生物系统的行为。</li><br />
<li style="margin-bottom: 0;"><strong>单细胞系统生物学：</strong> 利用 <strong>[[Single-cell Sequencing]]</strong> 解析细胞异质性。</li><br />
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作为 EMBO Press 家族的一员，MSB 在科学出版领域开创了多项透明化改革：<br />
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<th style="padding: 12px; border: 1px solid #cbd5e1; color: #0f172a; width: 30%;">政策名称</th><br />
<th style="padding: 12px; border: 1px solid #cbd5e1; color: #1e40af; width: 70%;">具体机制</th><br />
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<td style="padding: 10px; border: 1px solid #cbd5e1; font-weight: 600;">[[Transparent Review]]<br>(透明评审)</td><br />
<td style="padding: 10px; border: 1px solid #cbd5e1;">论文发表时，会同时附上<strong>匿名审稿人的意见</strong>、作者的回复信以及编辑的决策信。这极大地提高了审稿的负责度和透明度。</td><br />
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<td style="padding: 10px; border: 1px solid #cbd5e1; font-weight: 600;">[[Scooping Protection]]<br>(防抢发保护)</td><br />
<td style="padding: 10px; border: 1px solid #cbd5e1;">一旦稿件被 MSB 送审，在审稿期间如果其他期刊发表了类似成果，<strong>不会影响</strong>该稿件在 MSB 的发表资格。</td><br />
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<td style="padding: 10px; border: 1px solid #cbd5e1; font-weight: 600;">Source Data</td><br />
<td style="padding: 10px; border: 1px solid #cbd5e1;">强调数据的可重复性，要求作者上传生成图表的<strong>原始数据</strong>，并鼓励共享代码和模型。</td><br />
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MSB 是 <strong>[[EMBO Press]]</strong> 四大核心期刊之一。虽然所有 EMBO 期刊都关注分子生物学，但侧重点不同：<br />
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<li style="margin-bottom: 12px;"><strong>[[The EMBO Journal]]：</strong> 广泛的分子与细胞生物学，强调机制性洞察。</li><br />
<li style="margin-bottom: 12px;"><strong>[[Molecular Systems Biology]] (MSB)：</strong> 强调<strong>系统属性</strong>、定量分析和工程学方法。</li><br />
<li style="margin-bottom: 12px;"><strong>[[EMBO Reports]]：</strong> 涵盖分子生物学各个方面，同时发表关于科学与社会的评论。</li><br />
<li style="margin-bottom: 12px;"><strong>[[EMBO Molecular Medicine]]：</strong> 关注临床医学与分子机制的结合。</li><br />
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<span style="color: #0f172a; font-weight: bold; font-size: 1.05em; display: inline-block; margin-bottom: 15px;">学术参考文献 [Academic Review]</span><br />
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[1] <strong>Aebersold R. (2005).</strong> <em>Molecular Systems Biology: a new journal for a new biology.</em> <strong>[[Molecular Systems Biology]]</strong>. <br><br />
<span style="color: #475569;">[点评]：创刊社论，由知名蛋白质组学家 Ruedi Aebersold 撰写，阐述了系统生物学作为一门独立学科的崛起及创办该刊的必要性。</span><br />
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[2] <strong>Pulverer B. (2010).</strong> <em>Transparency, open access and the ongoing evolution of scientific publishing.</em> <strong>[[Nature Materials]]</strong>. <br><br />
<span style="color: #475569;">[点评]：EMBO Press 主编撰写的评论，详细介绍了透明评审流程 (Transparent Process) 的设计初衷和实施效果。</span><br />
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[3] <strong>Lemberger T. (2015).</strong> <em>10 years of Molecular Systems Biology.</em> <strong>[[Molecular Systems Biology]]</strong>. <br><br />
<span style="color: #475569;">[点评]：十周年纪念文章，回顾了过去十年系统生物学从“组学数据收集”向“定量建模与合成”的范式转变。</span><br />
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学术出版体系 · 知识图谱<br />
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<td style="width: 85px; background-color: #f8fafc; color: #334155; font-weight: 600; padding: 10px 12px; text-align: right; vertical-align: middle;">出版平台</td><br />
<td style="padding: 10px 15px; color: #334155;">[[EMBO Press]] • [[Wiley]] (合作方) • [[HighWire]] (托管)</td><br />
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<td style="width: 85px; background-color: #f8fafc; color: #334155; font-weight: 600; padding: 10px 12px; text-align: right; vertical-align: middle;">相关学科</td><br />
<td style="padding: 10px 15px; color: #334155;">[[Systems Biology]] • [[Synthetic Biology]] • [[Computational Biology]]</td><br />
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<td style="width: 85px; background-color: #f8fafc; color: #334155; font-weight: 600; padding: 10px 12px; text-align: right; vertical-align: middle;">竞争期刊</td><br />
<td style="padding: 10px 15px; color: #334155;">[[Nature Systems Biology]] (不存在, 近似为 Nat. Biotech) • [[Cell Systems]] • [[PLOS Computational Biology]]</td><br />
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