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J Exp Med - 版本历史
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<strong>J Exp Med</strong> 是顶级生物医学期刊 <strong>[[Journal of Experimental Medicine]]</strong>（实验医学杂志）的标准 <strong>ISO 4</strong> 文献缩写。该缩写广泛出现于 PubMed、Web of Science 等数据库的引文格式中。作为 <strong>[[洛克菲勒大学出版社]] (RUP)</strong> 的旗舰刊物，J Exp Med 在 <strong>[[免疫学]]</strong>、癌症生物学和生理学界拥有崇高的学术地位。它以发表“机制完整、数据详实”的长篇研究论文（Research Articles）而著称，历史上记录了包括 DNA 遗传本质验证、<strong>[[树突状细胞]]</strong> 发现以及 <strong>[[TLR4]]/[[MD-2]]</strong> 复合物鉴定等众多诺贝尔奖级的科学突破。<br />
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<div style="font-size: 1.2em; font-weight: bold; letter-spacing: 1.2px;">J Exp Med</div><br />
<div style="font-size: 0.7em; opacity: 0.85; margin-top: 4px; white-space: nowrap;">ISO Abbreviation (点击展开)</div><br />
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<div style="font-size: 0.8em; color: #64748b; margin-top: 12px; font-weight: 600;">生物医学引文的“金字招牌”</div><br />
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<th colspan="2" style="padding: 8px 12px; background-color: #e0f2fe; color: #1e40af; text-align: left; font-size: 0.9em; border-top: 1px solid #bae6fd;">引文索引数据</th><br />
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<th style="text-align: left; padding: 6px 12px; background-color: #f8fafc; color: #475569; border-bottom: 1px solid #e2e8f0; width: 40%;">全称</th><br />
<td style="padding: 6px 12px; border-bottom: 1px solid #e2e8f0; color: #0f172a;">Journal of Experimental Medicine</td><br />
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<th style="text-align: left; padding: 6px 12px; background-color: #f8fafc; color: #475569; border-bottom: 1px solid #e2e8f0;">ISSN (Print)</th><br />
<td style="padding: 6px 12px; border-bottom: 1px solid #e2e8f0; color: #1e40af;">0022-1007</td><br />
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<th style="text-align: left; padding: 6px 12px; background-color: #f8fafc; color: #475569; border-bottom: 1px solid #e2e8f0;">ISSN (Online)</th><br />
<td style="padding: 6px 12px; border-bottom: 1px solid #e2e8f0; color: #16a34a;">1540-9538</td><br />
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<th style="text-align: left; padding: 6px 12px; background-color: #f8fafc; color: #475569; border-bottom: 1px solid #e2e8f0;">NLM ID</th><br />
<td style="padding: 6px 12px; border-bottom: 1px solid #e2e8f0; color: #0f172a;">2985109R</td><br />
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<th colspan="2" style="padding: 8px 12px; background-color: #e0f2fe; color: #1e40af; text-align: left; font-size: 0.9em; border-top: 1px solid #bae6fd;">期刊计量指标</th><br />
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<td style="padding: 6px 12px; border-bottom: 1px solid #e2e8f0; color: #1e40af;">15.0+ (长期稳定)</td><br />
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<th style="text-align: left; padding: 6px 12px; background-color: #f8fafc; color: #475569; border-bottom: 1px solid #e2e8f0;">h-index</th><br />
<td style="padding: 6px 12px; border-bottom: 1px solid #e2e8f0; color: #0f172a;">&gt; 450</td><br />
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<th style="text-align: left; padding: 6px 12px; background-color: #f8fafc; color: #475569;">出版周期</th><br />
<td style="padding: 6px 12px; color: #e11d48;">月刊 (Monthly)</td><br />
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在阅读免疫学文献时，<strong>J Exp Med</strong> 是出现频率最高的引文缩写之一。了解其引用格式对于追踪原始数据至关重要。<br />
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<li style="margin-bottom: 12px;"><strong>标准引文格式：</strong> <br><span style="font-family: monospace; color: #e11d48;">Author(s). Title. J Exp Med. Year;Volume(Issue):Pages.</span></li><br />
<li style="margin-bottom: 12px;"><strong>常见变体：</strong><br />
<br>• <strong>J. Exp. Med.</strong> (带点缩写，常见于 EndNote 等软件)<br />
<br>• <strong>JEM</strong> (非正式口语或内部简写)</li><br />
<li style="margin-bottom: 0;"><strong>PMID 检索：</strong> 在 PubMed 中，使用搜索串 <code style="background: #e2e8f0; padding: 2px 5px; border-radius: 3px;">"J Exp Med"[Journal]</code> 可以限定搜索该刊的所有文章。</li><br />
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<h2 style="background: #f1f5f9; color: #0f172a; padding: 10px 18px; border-radius: 0 6px 6px 0; font-size: 1.25em; margin-top: 40px; border-left: 6px solid #0f172a; font-weight: bold;">J Exp Med 与内毒素研究</h2><br />
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该期刊是天然免疫识别（TLR）领域的“主战场”。根据我们前面构建的知识库，以下关键节点均首次发表于 J Exp Med：<br />
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<th style="padding: 12px; border: 1px solid #cbd5e1; color: #0f172a; width: 15%;">年份</th><br />
<th style="padding: 12px; border: 1px solid #cbd5e1; color: #1e40af; width: 30%;">第一作者</th><br />
<th style="padding: 12px; border: 1px solid #cbd5e1; color: #475569; width: 55%;">里程碑贡献</th><br />
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<td style="padding: 10px; border: 1px solid #cbd5e1; font-weight: 600;">1999</td><br />
<td style="padding: 10px; border: 1px solid #cbd5e1;"><strong>Shimazu R</strong></td><br />
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<a href="#" style="color: #0f172a; text-decoration: none; border-bottom: 1px dashed #94a3b8;">MD-2 的发现</a>。证明 TLR4 无法独自响应 LPS，必须与 MD-2 形成复合物。这是理解内毒素识别结构基础的关键一步。<br />
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<td style="padding: 10px; border: 1px solid #cbd5e1; font-weight: 600;">1973</td><br />
<td style="padding: 10px; border: 1px solid #cbd5e1;"><strong>Steinman RM</strong></td><br />
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<a href="#" style="color: #0f172a; text-decoration: none; border-bottom: 1px dashed #94a3b8;">树突状细胞 (DC)</a>。首次描述了这种形态独特、抗原呈递能力极强的细胞，连接了先天与适应性免疫。<br />
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<td style="padding: 10px; border: 1px solid #cbd5e1; font-weight: 600;">2001</td><br />
<td style="padding: 10px; border: 1px solid #cbd5e1;"><strong>Schromm AB</strong></td><br />
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<a href="#" style="color: #0f172a; text-decoration: none; border-bottom: 1px dashed #94a3b8;">MD-2 点突变</a>。发现 MD-2 上单个氨基酸的改变即可导致严重的免疫缺陷（LPS 无反应），揭示了临床脓毒症的遗传风险。<br />
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<span style="color: #0f172a; font-weight: bold; font-size: 1.05em; display: inline-block; margin-bottom: 15px;">J Exp Med 高被引文献示例 [References]</span><br />
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[1] <strong>Shimazu R, et al. (1999).</strong> <em>MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4.</em> <strong>[[J Exp Med]]</strong>; 189(11):1777-1782. <br><br />
<span style="color: #475569;">[PMID]: 10359581 | [引用数]: >2000</span><br />
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[2] <strong>Steinman RM, Cohn ZA. (1973).</strong> <em>Identification of a novel cell type in peripheral lymphoid organs of mice.</em> <strong>[[J Exp Med]]</strong>; 137(5):1142-1162. <br><br />
<span style="color: #475569;">[PMID]: 4573839 | [引用数]: >5000</span><br />
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[3] <strong>Marack P, et al. (2000).</strong> <em>The paradox of the immune specificity.</em> <strong>[[J Exp Med]]</strong>. <br><br />
<span style="color: #475569;">[点评]：JEM 不仅发表实验数据，也刊登极具深度的综述和观点文章，引领免疫学理论的发展。</span><br />
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文献情报系统 · 知识图谱<br />
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<td style="width: 85px; background-color: #f8fafc; color: #334155; font-weight: 600; padding: 10px 12px; text-align: right; vertical-align: middle;">ISO 缩写</td><br />
<td style="padding: 10px 15px; color: #334155;"><strong>J Exp Med</strong></td><br />
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<td style="width: 85px; background-color: #f8fafc; color: #334155; font-weight: 600; padding: 10px 12px; text-align: right; vertical-align: middle;">从属于</td><br />
<td style="padding: 10px 15px; color: #334155;">[[Journal of Experimental Medicine]] • [[洛克菲勒大学]]</td><br />
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<td style="width: 85px; background-color: #f8fafc; color: #334155; font-weight: 600; padding: 10px 12px; text-align: right; vertical-align: middle;">核心领域</td><br />
<td style="padding: 10px 15px; color: #334155;">[[免疫学]] • [[微生物学]] • [[生理学]]</td><br />
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