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<p>导航板-抑癌基因与癌基因</p> <p><b>新页面</b></p><div>{{Navbox<br /> | name = 抑癌基因与癌基因<br /> | title = [[肿瘤]] - [[新生物]]：[[肿瘤抑制基因|肿瘤抑制基因/蛋白]]与[[癌基因|癌基因/原癌基因]]<br /> | listclass = hlist<br /> | titlestyle = background:#e7dcc3<br /> | groupstyle = background-color: AntiqueWhite<br /> <br /> | group1 = [[配体 (生物化学)|配体]]<br /> | list1 = {{Navbox subgroup<br /> | groupstyle = background-color: AntiqueWhite<br /> <br /> | group1 = [[生长因子]]<br /> | list1 = <br /> * ONCO：[[血小板源性生长因子|c-Sis/PDGF]]<br /> * [[肝细胞生长因子|HGF]]<br /> <br /> }}<br /> <br /> | group2 = [[受体 (生物化学)|受体]]<br /> | list2 = {{Navbox subgroup<br /> | groupstyle = background-color: AntiqueWhite<br /> <br /> | group2 = [[Wnt信号通路]]<br /> | list2 =<br /> * TSP: [[CDH1 (基因)|CDH1]]<br /> <br /> |group3 = [[刺猬信号通路]]<br /> | list3 =<br /> * TSP：[[PTCH1]]<br /> <br /> | group4 = [[TGFβ信号通路]]<br /> | list4 =<br /> * TSP: [[TGFβ受体2]]<br /> <br /> | group5 = [[受体酪氨酸激酶]]<br /> | list5 =<br /> * ONCO: [[ErbB]]/[[表皮生长因子受体|c-ErbB]]<br /> ** [[HER2/neu]]<br /> ** [[ERBB3|Her 3]]<br /> * [[c-Met]]<br /> * [[RET原癌基因|c-Ret]]<br /> <br /> |group6 = [[JAK-STAT信号通路]]<br /> |list6 =<br /> * ONCO：[[CD117|c-Kit]]<br /> * [[CD135|Flt3]]<br /> <br /> }}<br /> <br /> | group3 = [[胞内信号肽与蛋白质|胞内信号P+P]]<br /> | list3 = {{Navbox subgroup<br /> | groupstyle = background-color: AntiqueWhite<br /> <br /> | group1 = [[Wnt信号通路]]<br /> | list1 =<br /> * ONCO：[[β-联蛋白]]<br /> * TSP：[[腺瘤性结肠息肉病|APC]]<br /> <br /> | group2 = [[TGFβ信号通路]]<br /> | list2 =<br /> * TSP：[[SMAD2]]<br /> * [[SMAD4]]<br /> <br /> | group3 = [[Akt/PKB信号通路]]<br /> | list3 =<br /> * TSP：[[PTEN (基因)|PTEN]]<br /> * ONCO：[[蛋白激酶B|c-Akt]]<br /> <br /> |group4 = [[河马信号通路]]<br /> |list4 = TSP：[[膜突样蛋白|神经纤维瘤蛋白2/膜突样蛋白]]<br /> <br /> | group5 = [[MAPK/ERK途径]]<br /> | list5 =<br /> * TSP：[[神经纤维瘤蛋白1]]<br /> * ONCO：[[Ras (蛋白)|c-Ras]]<br /> * [[HRAS]]<br /> * [[c-Raf]]<br /> <br /> | group6 = 其他/未知<br /> | list6 =<br /> * TSP: [[Maspin]]<br /> * ONCO: [[Src (基因)|c-Src]]<br /> <br /> }}<br /> <br /> | group4 = [[细胞核|核]]<br /> | list4 = {{Navbox subgroup<br /> | groupstyle = background-color: AntiqueWhite<br /> <br /> | group1 = [[细胞周期]]<br /> | list1 =<br /> * TSP：[[p53]]<br /> * [[视网膜母细胞瘤蛋白|pRb]]<br /> * [[WT1]]<br /> * [[P16 (基因)|p16]]/[[p14arf]]<br /> * ONCO：[[周期蛋白依赖性激酶4|CDK4]]<br /> * [[周期蛋白D]]<br /> * [[周期蛋白E]]<br /> <br /> | group2 = [[DNA修复]]/[[范科尼贫血|范科尼]]<br /> | list2 =<br /> * TSP：[[BRCA1]]<br /> * [[BRCA2]]<br /> <br /> |group3 = [[泛素连接酶]]<br /> |list3 =<br /> * TSP：[[视网膜血管瘤抑制因子|VHL]]<br /> * ONCO: [[CBL (基因)|CBL]]<br /> * [[Mdm2|MDM2]]<br /> <br /> |group4 = [[转录因子]]<br /> |list4 =<br /> * TSP: [[KLF6]]<br /> * ONCO: [[AP-1转录因子|AP-1]]<br /> ** [[c-Fos]]<br /> ** [[C-jun|c-Jun]]<br /> * [[Myc|c-Myc]]<br /> <br /> }}<br /> <br /> | group5 = [[线粒体]]<br /> | list5 =<br /> * [[凋亡抑制剂]]：[[SDHB]]<br /> * [[SDHD]]<br /> <br /> | group6 = 其他/未分组<br /> | list6 =<br /> * [[Bcl-2|c-Bcl-2]] - [[notch signaling|Notch]] - [[抑微管装配蛋白]]<br /> <br /> }}&lt;noinclude&gt;<br /> [[Category:信号转导模板]]<br /> &lt;/noinclude&gt;</div>

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